iPTMnet Report for Q70CQ4 (USP31)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q70CQ4 / UBP31_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 31
Gene Name Name: USP31
Synonyms:KIAA1203;
Organism Homo sapiens (Human)

PRO ID PR:Q70CQ4
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 31 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 31 that is encoded in the genome of human.
Short Label hUSP31
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q70CQ4 (USP31) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
T672 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus
Y696 Phosphorylation PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S887 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
T1022 Phosphorylation PhosphoSitePlus
T1023 O-Glycosylation GlyGen 30379171, 28411811
T1023 Phosphorylation PhosphoSitePlus
S1028 Phosphorylation PhosphoSitePlus
S1029 Phosphorylation PhosphoSitePlus
T1032 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T1056 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S1057 Phosphorylation PhosphoSitePlus
S1060 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation PhosphoSitePlus
S1103 Phosphorylation PhosphoSitePlus
S1106 Phosphorylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus
S1111 Phosphorylation PhosphoSitePlus
T1122 Phosphorylation PhosphoSitePlus
Y1123 Phosphorylation PhosphoSitePlus
S1126 Phosphorylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
S1169 Phosphorylation PhosphoSitePlus
S1174 Phosphorylation PhosphoSitePlus
S1178 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
S1206 O-Glycosylation GlyGen 30379171, 28411811
S1208 Phosphorylation PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
R1239 Methylation PhosphoSitePlus
S1241 Phosphorylation PhosphoSitePlus
T1247 Phosphorylation PhosphoSitePlus
K1264 Acetylation PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
S1313 Phosphorylation PhosphoSitePlus
S1318 Phosphorylation PhosphoSitePlus
S1322 Phosphorylation PhosphoSitePlus
S1323 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 19413330
S1052 Phosphorylation HPRD 17287340
T1056 Phosphorylation HPRD 17287340
S1241 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T345 I345 Biomuta DOID:4159 / skin cancer [ cosmic ]
S433 F433 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y696 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S807 C807 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S814 L814 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S887 L887 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S914 R914 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1029 F1029 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1056 A1056 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1060 F1060 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1089 F1089 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1106 F1106 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1109 F1109 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1111 L1111 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1126 F1126 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1178 F1178 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1208 I1208 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1239 W1239 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1241 L1241 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1322 L1322 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]