Protein Information

Cytoscape View

UniProt AC / UniProt ID Q70CQ1 / UBP49_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 49
Gene Name Name: USP49
Organism Homo sapiens (Human)

DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 49 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 49 that is encoded in the genome of human.
Short Label hUSP49
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q70CQ1 (USP49) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K93 Ubiquitination PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
R335 Methylation PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K93 N93 Biomuta DOID:1909 / melanoma [ cosmic ]
T154 M154 Biomuta DOID:5041 / esophageal cancer [ icgc ]