iPTMnet Report for Q70CQ1 (USP49)
Protein Information
| UniProt AC / UniProt ID | Q70CQ1 / UBP49_HUMAN |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 49 |
| Gene Name | Name: USP49 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q70CQ1 |
| PRO Name | ubiquitin carboxyl-terminal hydrolase 49 (human) |
| Definition | A ubiquitin carboxyl-terminal hydrolase 49 that is encoded in the genome of human. |
| Short Label | hUSP49 |
| Category | organism-gene |
Q70CQ1 (USP49) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R335 | Methylation | score1 | PhosphoSitePlus | |||
| T497 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K529 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K93 | N93 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T154 | M154 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| K306 | N306 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View