iPTMnet Report for Q70CQ1 (USP49)
Protein Information
UniProt AC / UniProt ID | Q70CQ1 / UBP49_HUMAN |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 49 |
Gene Name | Name: USP49 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q70CQ1 |
PRO Name | ubiquitin carboxyl-terminal hydrolase 49 (human) |
Definition | A ubiquitin carboxyl-terminal hydrolase 49 that is encoded in the genome of human. |
Short Label | hUSP49 |
Category | organism-gene |
Q70CQ1 (USP49) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
T116 | Phosphorylation | score1 | PhosphoSitePlus | |||
T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
R335 | Methylation | score1 | PhosphoSitePlus | |||
T497 | Phosphorylation | score1 | PhosphoSitePlus | |||
K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
K529 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K93 | N93 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T154 | M154 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
K306 | N306 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |