iPTMnet Report for Q709C8 (VPS13C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q709C8 / VP13C_HUMAN
Protein Name Intermembrane lipid transfer protein VPS13C
Gene Name Name: VPS13C
Synonyms:KIAA1421;
Organism Homo sapiens (Human)

PRO ID PR:Q709C8
DAG View
PRO Name intermembrane lipid transfer protein VPS13C (human)
Definition An intermembrane lipid transfer protein VPS13C that is encoded in the genome of human.
Short Label hVPS13C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q709C8 (VPS13C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K574 Methylation IEDB 32357974
K578 Ubiquitination PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus   UniProt 19690332
S619 Phosphorylation PhosphoSitePlus   UniProt 19690332
T624 Phosphorylation PhosphoSitePlus   UniProt 19690332
K695 Ubiquitination PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K797 Ubiquitination PhosphoSitePlus
K805 Acetylation PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
K823 Acetylation PhosphoSitePlus
Y827 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus   UniProt 23186163
S848 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
Y966 Phosphorylation PhosphoSitePlus
K973 Ubiquitination PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
K1062 Ubiquitination PhosphoSitePlus
K1122 Ubiquitination PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
S1228 Phosphorylation PhosphoSitePlus
K1230 Ubiquitination PhosphoSitePlus
Y1283 Phosphorylation PhosphoSitePlus
K1298 Ubiquitination PhosphoSitePlus
K1380 Ubiquitination PhosphoSitePlus
K1382 Ubiquitination PhosphoSitePlus
K1392 Ubiquitination PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
T1437 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1442 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Y1473 Phosphorylation PhosphoSitePlus
K1512 Ubiquitination PhosphoSitePlus
K1573 Ubiquitination PhosphoSitePlus
K1585 Ubiquitination PhosphoSitePlus
K1594 Ubiquitination PhosphoSitePlus
K1623 Ubiquitination PhosphoSitePlus
K1636 Ubiquitination PhosphoSitePlus
K1660 Ubiquitination PhosphoSitePlus
S1663 Phosphorylation PhosphoSitePlus
K1745 Ubiquitination PhosphoSitePlus
K1750 Ubiquitination PhosphoSitePlus
T1812 Phosphorylation PhosphoSitePlus
K1815 Ubiquitination PhosphoSitePlus
S1841 Phosphorylation PhosphoSitePlus
K1864 Ubiquitination PhosphoSitePlus
K1918 Ubiquitination PhosphoSitePlus
K1996 Acetylation PhosphoSitePlus
K1996 Ubiquitination PhosphoSitePlus
Y2032 Phosphorylation PhosphoSitePlus
K2033 Ubiquitination PhosphoSitePlus
K2036 Ubiquitination PhosphoSitePlus
S2071 Phosphorylation PhosphoSitePlus
K2077 Ubiquitination PhosphoSitePlus
K2095 Ubiquitination PhosphoSitePlus
S2098 Phosphorylation PhosphoSitePlus
S2139 Phosphorylation PhosphoSitePlus
K2155 Ubiquitination PhosphoSitePlus
K2233 Ubiquitination PhosphoSitePlus
C2289 Methylation IEDB 31844290
K2304 Ubiquitination PhosphoSitePlus
S2306 Phosphorylation PhosphoSitePlus
K2357 Ubiquitination PhosphoSitePlus
K2404 Ubiquitination PhosphoSitePlus
K2419 Ubiquitination PhosphoSitePlus
K2427 Ubiquitination PhosphoSitePlus
K2435 Ubiquitination PhosphoSitePlus
K2437 Ubiquitination PhosphoSitePlus
S2472 Phosphorylation PhosphoSitePlus
S2473 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2485 Phosphorylation PhosphoSitePlus
S2486 Phosphorylation PhosphoSitePlus
K2565 Ubiquitination PhosphoSitePlus
K2612 Ubiquitination PhosphoSitePlus
K2721 Ubiquitination PhosphoSitePlus
S2767 Phosphorylation PhosphoSitePlus
S2786 Phosphorylation PhosphoSitePlus
K2792 Ubiquitination PhosphoSitePlus
K2930 Ubiquitination PhosphoSitePlus
K3144 Ubiquitination PhosphoSitePlus
K3166 Ubiquitination PhosphoSitePlus
S3348 Phosphorylation PhosphoSitePlus
T3373 Phosphorylation PhosphoSitePlus
S3406 Phosphorylation PhosphoSitePlus
G3468 Methylation IEDB 32357974
S3484 Phosphorylation PhosphoSitePlus
K3487 Ubiquitination PhosphoSitePlus
K3496 Ubiquitination PhosphoSitePlus
Y3498 Phosphorylation PhosphoSitePlus
K3501 Ubiquitination PhosphoSitePlus
S3516 Phosphorylation PhosphoSitePlus
R3519 Methylation PhosphoSitePlus
R3526 Methylation PhosphoSitePlus   UniProt 24129315
K3538 Acetylation PhosphoSitePlus   UniProt 19608861
K3538 Ubiquitination PhosphoSitePlus
K3545 Methylation PhosphoSitePlus
K3545 Ubiquitination PhosphoSitePlus
K3553 Methylation PhosphoSitePlus
K3553 Ubiquitination PhosphoSitePlus
K3557 Ubiquitination PhosphoSitePlus
S3587 Phosphorylation PhosphoSitePlus
S3614 Phosphorylation PhosphoSitePlus
K3625 Ubiquitination PhosphoSitePlus
K3626 Acetylation PhosphoSitePlus
S3641 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3642 Ubiquitination PhosphoSitePlus
T3649 Phosphorylation PhosphoSitePlus
K3714 Ubiquitination PhosphoSitePlus
S3743 Phosphorylation PhosphoSitePlus
S3753 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T542 Phosphorylation HPRD 18452278
T562 Phosphorylation HPRD 20068231
T734 Phosphorylation HPRD 19413330
S736 Phosphorylation HPRD 20166139
S737 Phosphorylation HPRD 19413330, 20058876
T1437 Phosphorylation HPRD 17081983
S1442 Phosphorylation HPRD 17081983
S1630 Phosphorylation HPRD 20068231
S1663 Phosphorylation HPRD 20068231
T1876 Phosphorylation HPRD 20068231
T1902 Phosphorylation HPRD 20068231
S2485 Phosphorylation HPRD 20068231
T3021 Phosphorylation HPRD 20068231
S3641 Phosphorylation HPRD 20068231
T3649 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T542 Phosphorylation HPRD 18452278
T562 Phosphorylation HPRD 20068231
T734 Phosphorylation HPRD 19413330
S736 Phosphorylation HPRD 20166139
S737 Phosphorylation HPRD 19413330, 20058876
T1437 Phosphorylation HPRD 17081983
S1442 Phosphorylation HPRD 17081983
S1630 Phosphorylation HPRD 20068231
S1663 Phosphorylation HPRD 20068231
T1876 Phosphorylation HPRD 20068231
T1902 Phosphorylation HPRD 20068231
S2485 Phosphorylation HPRD 20068231
T3021 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T499 Phosphorylation HPRD 18452278
T519 Phosphorylation HPRD 20068231
T691 Phosphorylation HPRD 19413330
S693 Phosphorylation HPRD 20166139
S694 Phosphorylation HPRD 19413330, 20058876
T1394 Phosphorylation HPRD 17081983
S1399 Phosphorylation HPRD 17081983
S1587 Phosphorylation HPRD 20068231
S1620 Phosphorylation HPRD 20068231
T1833 Phosphorylation HPRD 20068231
T1859 Phosphorylation HPRD 20068231
S2442 Phosphorylation HPRD 20068231
T2978 Phosphorylation HPRD 20068231
S3598 Phosphorylation HPRD 20068231
T3606 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T499 Phosphorylation HPRD 18452278
T519 Phosphorylation HPRD 20068231
T691 Phosphorylation HPRD 19413330
S693 Phosphorylation HPRD 20166139
S694 Phosphorylation HPRD 19413330, 20058876
T1394 Phosphorylation HPRD 17081983
S1399 Phosphorylation HPRD 17081983
S1587 Phosphorylation HPRD 20068231
S1620 Phosphorylation HPRD 20068231
T1833 Phosphorylation HPRD 20068231
T1859 Phosphorylation HPRD 20068231
S2442 Phosphorylation HPRD 20068231
T2978 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K56 T56 Biomuta DOID:363 / uterine cancer [ cosmic ]
S170 L170 Biomuta DOID:1324 / lung cancer [ cosmic ]
S490 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
T499 M499 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T542 M542 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T614 S614 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S693 * Biomuta DOID:363 / uterine cancer [ cosmic, cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K732 T732 Biomuta DOID:363 / uterine cancer [ cosmic ]
K732 N732 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S736 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S807 P807 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S1398 F1398 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1400 P1400 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1400 L1400 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1620 C1620 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1663 C1663 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1841 F1841 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1864 R1864 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S2098 C2098 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2306 L2306 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2486 F2486 Biomuta DOID:4159 / skin cancer [ cosmic ]
K3166 T3166 Biomuta DOID:363 / uterine cancer [ cosmic ]
R3526 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S3614 Y3614 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K3625 N3625 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S3743 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]