iPTMnet Report for Q6ZWH5 (NEK10)
Protein Information
| UniProt AC / UniProt ID | Q6ZWH5 / NEK10_HUMAN |
| Protein Name | Serine/threonine-protein kinase Nek10 |
| Gene Name | Name: NEK10 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6ZWH5 |
| PRO Name | serine/threonine-protein kinase Nek10 (human) |
| Definition | A serine/threonine-protein kinase Nek10 that is encoded in the genome of human. |
| Short Label | hNEK10 |
| Category | organism-gene |
DAG ViewQ6ZWH5 (NEK10) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S358 | Phosphorylation | score0 | RLIMS-P | 31124786 | ||
| Y583 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y590 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y591 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y644 | Phosphorylation | score0 | RLIMS-P | 31124786 | ||
| S1086 | Phosphorylation | score1 | IEDB | 35494241 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y591 | F591 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y591 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
