Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZWE6 / PKHM3_HUMAN
Protein Name Pleckstrin homology domain-containing family M member 3
Gene Name Name: PLEKHM3
Synonyms:DAPR;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZWE6
DAG View
PRO Name pleckstrin homology domain-containing family M member 3 (human)
Definition A pleckstrin homology domain-containing family M member 3 that is encoded in the genome of human.
Short Label hPLEKHM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZWE6 (PLEKHM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
T102 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
Y563 Phosphorylation PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus
T752 Phosphorylation PhosphoSitePlus
T761 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S132 Phosphorylation HPRD 19651622
Y563 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 N10 Biomuta DOID:3070 / malignant glioma [ tcga ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S10 R10 Biomuta DOID:1909 / melanoma [ cosmic ] DOID:3571 / liver cancer [ icgc ]
K77 E77 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S107 F107 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T140 N140 Biomuta DOID:3571 / liver cancer [ icgc ]
S150 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T668 N668 Biomuta DOID:3571 / liver cancer [ icgc ]