iPTMnet Report for Q6ZVM7 (TOM1L2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZVM7 / TM1L2_HUMAN
Protein Name TOM1-like protein 2
Gene Name Name: TOM1L2
Organism Homo sapiens (Human)

PRO ID PR:Q6ZVM7
DAG View
PRO Name TOM1-like protein 2 (human)
Definition A TOM1-like protein 2 that is encoded in the genome of human.
Short Label hTOM1L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZVM7 (TOM1L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S160 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T164 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S168 Phosphorylation PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
Y192 Phosphorylation phospho.ELM   PhosphoSitePlus 15951569
S193 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S160 Phosphorylation HPRD 19651622, 18669648, 20068231
T164 Phosphorylation HPRD 19651622, 18669648, 20068231
T177 Phosphorylation HPRD 18212344
Y200 Phosphorylation HPRD 15951569
Y404 Phosphorylation HPRD 19901323, 17389395
S423 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S110 Phosphorylation HPRD 19651622, 18669648, 20068231
T114 Phosphorylation HPRD 19651622, 18669648, 20068231
T127 Phosphorylation HPRD 18212344
Y150 Phosphorylation HPRD 15951569
Y354 Phosphorylation HPRD 19901323, 17389395
S373 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K116 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S110 A110 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T114 I114 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S160 A160 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T164 I164 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S193 F193 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S394 C394 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S394 F394 Biomuta DOID:4159 / skin cancer [ cosmic ]
T401 M401 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T401 A401 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S479 L479 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]