iPTMnet Report for Q6ZUJ8 (PIK3AP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZUJ8 / BCAP_HUMAN
Protein Name Phosphoinositide 3-kinase adapter protein 1
Gene Name Name: PIK3AP1
Synonyms:BCAP;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZUJ8
DAG View
PRO Name phosphoinositide 3-kinase adapter protein 1 (human)
Definition A phosphoinositide 3-kinase adapter protein 1 that is encoded in the genome of human.
Short Label hPIK3AP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZUJ8 (PIK3AP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C10 Methylation IEDB 31844290
Y133 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
Y263 Phosphorylation PRO
K349 Ubiquitination PhosphoSitePlus
Y419 Phosphorylation PRO   PhosphoSitePlus
Y444 Phosphorylation PRO
Y459 Phosphorylation PRO
K487 Ubiquitination PhosphoSitePlus
Y513 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15893754
Y513 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 15893754
Y553 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15893754
Y553 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 15893754
S562 Phosphorylation PhosphoSitePlus
Y570 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15893754
Y570 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 15893754
S575 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
Y594 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15893754
Y594 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 15893754
K601 Ubiquitination PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus   UniProt 23186163
S656 Phosphorylation PhosphoSitePlus
T658 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
Y694 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15893754
Y694 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 15893754
S696 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
T716 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus   UniProt 24275569
S757 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
T768 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y570 Phosphorylation HPRD 16497976
S642 Phosphorylation HPRD 20166139
S656 Phosphorylation HPRD 20166139
Y694 Phosphorylation HPRD 18083107, 17693683


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048768 (hPIK3AP1/Phos:1) pY263,pY419,pY444,pY459 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S145 Y145 Biomuta DOID:4159 / skin cancer [ cosmic ]
S174 L174 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y459 C459 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S562 I562 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S592 N592 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y594 C594 Biomuta DOID:3571 / liver cancer [ cosmic ]
S640 L640 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T658 A658 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S682 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S682 L682 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S696 T696 Biomuta DOID:1324 / lung cancer [ cosmic ]
S701 N701 Biomuta DOID:4159 / skin cancer [ cosmic ]
S718 I718 Biomuta DOID:363 / uterine cancer [ icgc ]