iPTMnet Report for Q6ZS81 (WDFY4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZS81 / WDFY4_HUMAN
Protein Name WD repeat- and FYVE domain-containing protein 4
Gene Name Name: WDFY4
Synonyms:C10orf64,KIAA1607;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZS81
DAG View
PRO Name WD repeat- and FYVE domain-containing protein 4 (human)
Definition A WD repeat- and FYVE domain-containing protein 4 that is encoded in the genome of human.
Short Label hWDFY4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZS81 (WDFY4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T240 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
T1085 Phosphorylation PhosphoSitePlus
K1174 Acetylation PhosphoSitePlus
T1237 Phosphorylation PhosphoSitePlus
Y1238 Phosphorylation PhosphoSitePlus
K1317 Ubiquitination PhosphoSitePlus
T1346 Phosphorylation PhosphoSitePlus
S1688 Phosphorylation PhosphoSitePlus
S1962 Phosphorylation PhosphoSitePlus
S2202 Phosphorylation PhosphoSitePlus
Y2230 Phosphorylation PhosphoSitePlus
S2305 Phosphorylation PhosphoSitePlus
C2419 Methylation IEDB 31844290
S2454 Phosphorylation PhosphoSitePlus
T2455 Phosphorylation PhosphoSitePlus
S2464 Phosphorylation PhosphoSitePlus
Y2465 Phosphorylation PhosphoSitePlus
Y2631 Phosphorylation PhosphoSitePlus
S2686 Phosphorylation PhosphoSitePlus
S2789 Phosphorylation PhosphoSitePlus
T2791 Phosphorylation PhosphoSitePlus
S2804 Phosphorylation PhosphoSitePlus
T2815 Phosphorylation PhosphoSitePlus
S3123 Phosphorylation PhosphoSitePlus
K3131 Ubiquitination PhosphoSitePlus
S3136 Phosphorylation PhosphoSitePlus
S3142 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S254 R254 Biomuta DOID:1324 / lung cancer [ icgc ]
S477 T477 Biomuta DOID:3571 / liver cancer [ cosmic ]
S481 F481 Biomuta DOID:4159 / skin cancer [ cosmic ]
S507 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T634 I634 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1317 N1317 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1688 P1688 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1962 F1962 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2464 N2464 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y2465 C2465 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2789 I2789 Biomuta DOID:363 / uterine cancer [ cosmic ]
S3136 I3136 Biomuta DOID:363 / uterine cancer [ icgc ]