iPTMnet Report for Q6ZRS2 (SRCAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZRS2 / SRCAP_HUMAN
Protein Name Helicase SRCAP
Gene Name Name: SRCAP
Synonyms:KIAA0309;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZRS2
DAG View
PRO Name helicase SRCAP (human)
Definition A helicase SRCAP that is encoded in the genome of human.
Short Label hSRCAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZRS2 (SRCAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S196 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 35254053
S196 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
T576 Phosphorylation PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
C721 Methylation IEDB 31844290
K752 Ubiquitination PhosphoSitePlus
K827 Ubiquitination PhosphoSitePlus
K847 Acetylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
S1048 O-Glycosylation GlyGen 29351928
S1054 O-Glycosylation GlyGen 29351928
R1098 Methylation IEDB 27503676
S1124 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 35254053
S1125 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 35254053
S1126 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 35254053
S1172 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1186 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...34725712, 35132862, 30620550, 34019948, 31492838, 35289036, 35254053
S1186 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
K1205 Acetylation PhosphoSitePlus
R1224 Methylation PhosphoSitePlus
R1232 Methylation PhosphoSitePlus
R1314 Methylation PhosphoSitePlus
R1318 Methylation PhosphoSitePlus
T1322 Phosphorylation PhosphoSitePlus
R1332 Methylation IEDB 27503676
S1380 O-Glycosylation GlyGen 29351928
S1382 O-Glycosylation GlyGen 29351928
S1386 O-Glycosylation GlyGen 29351928
S1388 O-Glycosylation GlyGen 29351928
S1758 Phosphorylation PhosphoSitePlus
T1813 Phosphorylation IEDB 32387766
S1818 Phosphorylation IEDB 32387766
S1826 Phosphorylation PhosphoSitePlus
S1828 Phosphorylation PhosphoSitePlus
K1845 Ubiquitination PhosphoSitePlus
S1855 Phosphorylation PhosphoSitePlus
S1859 Phosphorylation PhosphoSitePlus
S1862 Phosphorylation PhosphoSitePlus
S1882 Phosphorylation PhosphoSitePlus
K1892 Ubiquitination PhosphoSitePlus
S1940 Phosphorylation PhosphoSitePlus
T2093 O-Glycosylation GlyGen 29351928
S2224 Phosphorylation PhosphoSitePlus
T2258 Phosphorylation PhosphoSitePlus
T2310 Phosphorylation PhosphoSitePlus
K2350 Ubiquitination PhosphoSitePlus
T2374 Phosphorylation PhosphoSitePlus
K2384 Methylation PhosphoSitePlus
T2406 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...32574038, 34725712, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550
T2406 Phosphorylation PhosphoSitePlus
T2412 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...32574038, 34725712, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550
T2412 Phosphorylation PhosphoSitePlus
S2416 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 34846842, 33214551, ...32938750, 35254053, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 30620550, 31492838, 23584533, 35289036, 29351928, 29237092, 20068230
T2420 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...32574038, 34725712, 34019948, 35254053, 35132862, 31492838, 29351928, 35289036, 30620550
T2423 Phosphorylation PhosphoSitePlus
T2424 Phosphorylation PhosphoSitePlus
T2425 Phosphorylation PhosphoSitePlus
S2430 Phosphorylation PhosphoSitePlus
S2524 Phosphorylation IEDB 27869121
T2682 Phosphorylation PhosphoSitePlus
T2684 Phosphorylation PhosphoSitePlus
T2724 Phosphorylation PhosphoSitePlus
S2725 Phosphorylation PhosphoSitePlus
R2771 Methylation PhosphoSitePlus
S2787 Phosphorylation PhosphoSitePlus
S2790 Phosphorylation PhosphoSitePlus
T2836 Phosphorylation PhosphoSitePlus
S2840 Phosphorylation PhosphoSitePlus
T2852 Phosphorylation PhosphoSitePlus
S2869 Phosphorylation PhosphoSitePlus
S2932 O-Glycosylation GlyGen 29351928
S2932 Phosphorylation PhosphoSitePlus
S3016 Phosphorylation PhosphoSitePlus
S3020 Phosphorylation PhosphoSitePlus
S3050 Phosphorylation PhosphoSitePlus
S3053 Phosphorylation PhosphoSitePlus
S3054 Phosphorylation PhosphoSitePlus
S3055 Phosphorylation PhosphoSitePlus
R3077 Methylation PhosphoSitePlus
T3107 Phosphorylation PhosphoSitePlus
T3114 Phosphorylation PhosphoSitePlus
S3126 Phosphorylation PhosphoSitePlus
R3140 Methylation PhosphoSitePlus
S3148 Phosphorylation PhosphoSitePlus
S3161 Phosphorylation PhosphoSitePlus
S3168 Phosphorylation PhosphoSitePlus
S3172 Phosphorylation PhosphoSitePlus
S3177 Phosphorylation PhosphoSitePlus
R3224 Methylation PhosphoSitePlus
R3226 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S248 Phosphorylation HPRD 17525332
S258 Phosphorylation HPRD 19413330
S348 Phosphorylation HPRD 20068231
S562 Phosphorylation HPRD 18452278
S568 Phosphorylation HPRD 18452278
T572 Phosphorylation HPRD 20068231
S1172 Phosphorylation HPRD 20068231
S1859 Phosphorylation HPRD 19651622
T2258 Phosphorylation HPRD 17525332
T2425 Phosphorylation HPRD 18669648
S2430 Phosphorylation HPRD 18669648
T2724 Phosphorylation HPRD 20068231
S2787 Phosphorylation HPRD 19413330, 18669648
S2790 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S2840 Phosphorylation HPRD 17081983, 20068231
T2852 Phosphorylation HPRD 20068231
S2869 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231
S3016 Phosphorylation HPRD 19651622, 20068231
S3148 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S3161 Phosphorylation HPRD 18452278
S3168 Phosphorylation HPRD 19413330, 18452278
S3177 Phosphorylation HPRD 19413330, 18452278
T3199 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S258 N258 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S348 F348 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T577 A577 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K703 Q703 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C721 S721 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K827 E827 Biomuta DOID:184 / bone cancer [ cosmic ]
T979 A979 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R1098 W1098 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1098 P1098 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1125 C1125 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S1192 L1192 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R1232 H1232 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R1318 Q1318 Biomuta DOID:363 / uterine cancer [ icgc ]
R1332 L1332 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1826 L1826 Biomuta [ cosmic ]
S1828 F1828 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1859 I1859 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1892 T1892 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2224 F2224 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2374 I2374 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T2406 I2406 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2412 I2412 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T2412 S2412 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T2423 I2423 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T2424 A2424 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R2771 L2771 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R2771 Q2771 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2771 W2771 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S2787 N2787 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2840 N2840 Biomuta DOID:1324 / lung cancer [ cosmic ]
S3016 L3016 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3054 F3054 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S3055 F3055 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R3077 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T3114 I3114 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3148 R3148 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S3161 G3161 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R3226 H3226 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R3226 C3226 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]