iPTMnet Report for Q6ZR52 (ZNF493)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZR52 / ZN493_HUMAN
Protein Name Zinc finger protein 493
Gene Name Name: ZNF493
Organism Homo sapiens (Human)

PRO ID PR:Q6ZR52
DAG View
PRO Name zinc finger protein 493 (human)
Definition A zinc finger protein 493 that is encoded in the genome of human.
Short Label hZNF493
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZR52 (ZNF493) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T20 Phosphorylation PhosphoSitePlus
T21 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
K194 Sumoylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K250 Sumoylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K306 Sumoylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K331 Sumoylation PhosphoSitePlus
K334 Sumoylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K359 Sumoylation PhosphoSitePlus
K362 Sumoylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K390 Acetylation PhosphoSitePlus
K390 Sumoylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K418 Sumoylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K474 Sumoylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K502 Sumoylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
K530 Sumoylation PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
T543 Phosphorylation PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K555 Sumoylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
T608 Phosphorylation PhosphoSitePlus
Y613 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 I23 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K33 N33 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y112 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S117 Y117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K194 T194 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T244 N244 Biomuta DOID:1319 / brain cancer [ icgc ]
K266 E266 Biomuta [ cosmic ]
K266 R266 Biomuta [ cosmic ]
T300 S300 Biomuta DOID:1319 / brain cancer [ cosmic ]
K362 T362 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K415 N415 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K424 N424 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K474 R474 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K493 Q493 Biomuta DOID:10283 / prostate cancer [ icgc ]
K493 R493 Biomuta DOID:3571 / liver cancer [ cosmic ]
K493 I493 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K493 M493 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K493 N493 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K499 N499 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K502 R502 Biomuta DOID:1319 / brain cancer [ icgc ]
K530 T530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T543 S543 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T580 I580 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T580 S580 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T608 N608 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T608 S608 Biomuta DOID:2531 / hematologic cancer [ cosmic ]