iPTMnet Report for Q6ZNJ1 (NBEAL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZNJ1 / NBEL2_HUMAN
Protein Name Neurobeachin-like protein 2
Gene Name Name: NBEAL2
Synonyms:KIAA0540;ORFNames:UNQ253/PRO290;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZNJ1
DAG View
PRO Name neurobeachin-like protein 2 (human)
Definition A neurobeachin-like protein 2 that is encoded in the genome of human.
Short Label hNBEAL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZNJ1 (NBEAL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
Y729 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
T746 O-Glycosylation GlyGen 35132862, 35254053
S757 Phosphorylation PhosphoSitePlus
T764 Phosphorylation PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
K907 Ubiquitination PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K1059 Ubiquitination PhosphoSitePlus
K1181 Ubiquitination PhosphoSitePlus
T1298 Phosphorylation PhosphoSitePlus
S1301 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
T1322 Phosphorylation PhosphoSitePlus
T1381 Phosphorylation PhosphoSitePlus
S1384 Phosphorylation PhosphoSitePlus
T1388 Phosphorylation PhosphoSitePlus
S1390 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
K1493 Ubiquitination PhosphoSitePlus
Y1600 Phosphorylation IEDB 35494241
K1624 Ubiquitination PhosphoSitePlus
S1647 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648
K1716 Ubiquitination PhosphoSitePlus
C1814 Methylation IEDB 31844290
K1828 Ubiquitination PhosphoSitePlus
S1831 Phosphorylation PhosphoSitePlus
K1841 Ubiquitination PhosphoSitePlus
T1867 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1869 Phosphorylation PhosphoSitePlus
K1880 Ubiquitination PhosphoSitePlus
T1886 Phosphorylation PhosphoSitePlus
T1906 Phosphorylation IEDB 35494241
T2008 Phosphorylation PhosphoSitePlus
T2009 Phosphorylation PhosphoSitePlus
S2012 Phosphorylation PhosphoSitePlus
S2013 Phosphorylation PhosphoSitePlus
T2017 Phosphorylation PhosphoSitePlus
S2054 Phosphorylation PhosphoSitePlus
K2067 Ubiquitination PhosphoSitePlus
K2124 Ubiquitination PhosphoSitePlus
K2132 Ubiquitination PhosphoSitePlus
K2140 Ubiquitination PhosphoSitePlus
K2153 Ubiquitination PhosphoSitePlus
C2190 Methylation IEDB 31844290
S2208 Phosphorylation PhosphoSitePlus
K2321 Ubiquitination PhosphoSitePlus
K2339 Ubiquitination PhosphoSitePlus
Y2432 Phosphorylation PhosphoSitePlus
S2434 Phosphorylation PhosphoSitePlus
S2436 Phosphorylation PhosphoSitePlus
K2437 Ubiquitination PhosphoSitePlus
T2440 Phosphorylation PhosphoSitePlus
K2445 Ubiquitination PhosphoSitePlus
K2472 Ubiquitination PhosphoSitePlus
K2697 Ubiquitination PhosphoSitePlus
S2734 Phosphorylation PhosphoSitePlus
S2735 Phosphorylation PhosphoSitePlus
S2739 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S2742 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2743 Phosphorylation PhosphoSitePlus
T2746 Phosphorylation PhosphoSitePlus
Y2748 Phosphorylation PhosphoSitePlus
T2751 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S757 Phosphorylation HPRD 18669648
T1298 Phosphorylation HPRD 20058876
S1301 Phosphorylation HPRD 20058876
T1322 Phosphorylation HPRD 20058876
S1410 Phosphorylation HPRD 20058876
S1503 Phosphorylation HPRD 20068231
S1647 Phosphorylation HPRD 18691976, 18669648, 20068231
T1867 Phosphorylation HPRD 18691976, 18669648, 20058876
S2012 Phosphorylation HPRD 18691976
S2013 Phosphorylation HPRD 18691976
S2739 Phosphorylation HPRD 19651622, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K344 M344 Biomuta DOID:2174 / ocular cancer [ tcga ]
K399 N399 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
Y729 C729 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T764 A764 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1600 C1600 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1600 F1600 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1716 R1716 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1831 R1831 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2054 F2054 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K2339 R2339 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2434 I2434 Biomuta DOID:1324 / lung cancer [ cosmic ]
K2697 N2697 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T2751 A2751 Biomuta DOID:9256 / colorectal cancer [ cosmic ]