iPTMnet Report for Q6ZNB6 (NFXL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZNB6 / NFXL1_HUMAN
Protein Name NF-X1-type zinc finger protein NFXL1
Gene Name Name: NFXL1
Synonyms:OZFP;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZNB6
DAG View
PRO Name NF-X1-type zinc finger protein NFXL1 (human)
Definition An NF-X1-type zinc finger protein NFXL1 that is encoded in the genome of human.
Short Label hNFXL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZNB6 (NFXL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
R18 Methylation PhosphoSitePlus
R31 Methylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
T49 Phosphorylation phospho.ELM 18669648
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T57 O-Glycosylation GlyGen 28657654, 35254053
S65 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S69 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T74 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S106 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
S107 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
S108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648, 17081983
S109 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
K122 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
C234 Methylation IEDB 31844290
K292 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
C460 Methylation IEDB 31844290
K462 Ubiquitination PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
Y745 Phosphorylation PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K780 Ubiquitination PhosphoSitePlus
K795 Ubiquitination PhosphoSitePlus
K807 Ubiquitination PhosphoSitePlus
K813 Ubiquitination PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K843 Ubiquitination PhosphoSitePlus
K850 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T49 Phosphorylation HPRD 18669648
S50 Phosphorylation HPRD 18669648, 20068231
S65 Phosphorylation HPRD 18669648, 20068231
S69 Phosphorylation HPRD 18669648, 20068231
S106 Phosphorylation HPRD 19651622, 18669648, 17081983
S107 Phosphorylation HPRD 19651622, 18669648, 17081983
S108 Phosphorylation HPRD 19651622, 18669648, 17081983
S109 Phosphorylation HPRD 19651622, 18669648, 17081983
Y518 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S106 N106 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S109 C109 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K122 R122 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K122 Q122 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C234 F234 Biomuta DOID:363 / uterine cancer [ icgc ]
S331 N331 Biomuta DOID:1319 / brain cancer [ cosmic ]
K402 R402 Biomuta DOID:3571 / liver cancer [ cosmic ]
C460 Y460 Biomuta DOID:184 / bone cancer [ cosmic ]
K740 N740 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y745 H745 Biomuta DOID:263 / kidney cancer [ cosmic ]
K807 E807 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S835 C835 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K838 T838 Biomuta DOID:363 / uterine cancer [ icgc ]