iPTMnet Report for Q6ZNA4 (RNF111)
Protein Information
UniProt AC / UniProt ID | Q6ZNA4 / RN111_HUMAN |
Protein Name | E3 ubiquitin-protein ligase Arkadia |
Gene Name | Name: RNF111 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6ZNA4 |
PRO Name | E3 ubiquitin-protein ligase Arkadia (human) |
Definition | An E3 ubiquitin-protein ligase Arkadia that is encoded in the genome of human. |
Short Label | hRNF111 |
Category | organism-gene |
Q6ZNA4 (RNF111) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K19 | Sumoylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K34 | Sumoylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
K47 | Sumoylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
K73 | Sumoylation | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
K173 | Sumoylation | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score1 | PhosphoSitePlus | |||
S579 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y783 | Phosphorylation | score1 | PhosphoSitePlus | |||
R861 | Methylation | score1 | PhosphoSitePlus | |||
R895 | Methylation | score1 | PhosphoSitePlus | |||
S898 | Phosphorylation | score1 | PhosphoSitePlus | |||
T901 | Phosphorylation | score1 | PhosphoSitePlus | |||
K927 | Sumoylation | score1 | PhosphoSitePlus | |||
K927 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K87 | Q87 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S339 | L339 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S354 | F354 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
R861 | C861 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
R861 | H861 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R895 | C895 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R895 | H895 | Biomuta | DOID:363 / uterine cancer [ icgc ] |