Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZN66 / GBP6_HUMAN
Protein Name Guanylate-binding protein 6
Gene Name Name: GBP6
Organism Homo sapiens (Human)

PRO ID PR:Q6ZN66
DAG View
PRO Name guanylate-binding protein 6 (human)
Definition A guanylate-binding protein 6 that is encoded in the genome of human.
Short Label hGBP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZN66 (GBP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y199 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
K554 Methylation PhosphoSitePlus
K565 Methylation PhosphoSitePlus
K627 Methylation PhosphoSitePlus
K628 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K554 N554 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K627 N627 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K628 E628 Biomuta DOID:2531 / hematologic cancer [ cosmic ]