iPTMnet Report for Q6ZMZ0 (RNF19B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZMZ0 / RN19B_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF19B
Gene Name Name: RNF19B
Synonyms:IBRDC3,NKLAM;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZMZ0
DAG View
PRO Name E3 ubiquitin-protein ligase RNF19B (human)
Definition An E3 ubiquitin-protein ligase RNF19B that is encoded in the genome of human.
Short Label hRNF19B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZMZ0 (RNF19B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
C203 Methylation IEDB 31844290
S270 Phosphorylation IEDB 29493099
K338 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
T554 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
T698 Phosphorylation PhosphoSitePlus
S706 Phosphorylation PhosphoSitePlus
T721 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K267 Ubiquitination PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K166 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K267 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 W14 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
K187 R187 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S270 L270 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S273 R273 Biomuta [ cosmic ]
T698 I698 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]