Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZMT9 / DTHD1_HUMAN
Protein Name Death domain-containing protein 1
Gene Name Name: DTHD1
Organism Homo sapiens (Human)

PRO ID PR:Q6ZMT9
DAG View
PRO Name death domain-containing protein 1 (human)
Definition A death domain-containing protein 1 that is encoded in the genome of human.
Short Label hDTHD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZMT9 (DTHD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
T103 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
K162 Methylation PhosphoSitePlus
K164 Methylation PhosphoSitePlus
R246 Methylation PhosphoSitePlus
R248 Methylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
Y620 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S272 L272 Biomuta DOID:4159 / skin cancer [ cosmic ]
T283 N283 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]