iPTMnet Report for Q6ZMT1 (STAC2)
Protein Information
| UniProt AC / UniProt ID | Q6ZMT1 / STAC2_HUMAN |
| Protein Name | SH3 and cysteine-rich domain-containing protein 2 |
| Gene Name | Name: STAC2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6ZMT1 |
| PRO Name | SH3 and cysteine-rich domain-containing protein 2 (human) |
| Definition | An SH3 and cysteine-rich domain-containing protein 2 that is encoded in the genome of human. |
| Short Label | hSTAC2 |
| Category | organism-gene |
Q6ZMT1 (STAC2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T409 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S39 | F39 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| S78 | P78 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S78 | F78 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S92 | F92 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S92 | T92 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S122 | T122 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S174 | T174 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S192 | F192 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S192 | Y192 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T225 | P225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S232 | N232 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |
DAG View