iPTMnet Report for Q6ZMQ8 (AATK)
Protein Information
| UniProt AC / UniProt ID | Q6ZMQ8 / LMTK1_HUMAN |
| Protein Name | Serine/threonine-protein kinase LMTK1 |
| Gene Name | Name: AATK Synonyms:AATYK,KIAA0641,LMR1,LMTK1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6ZMQ8 |
| PRO Name | serine/threonine-protein kinase LMTK1 (human) |
| Definition | A serine/threonine-protein kinase LMTK1 that is encoded in the genome of human. |
| Short Label | hAATK |
| Category | organism-gene |
Q6ZMQ8 (AATK) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K57 | Acetylation | score1 | PhosphoSitePlus | |||
| Y73 | Phosphorylation | P06241 (FYN) | score2 | neXtProt | 18691334 | |
| S81 | Phosphorylation | score3 | neXtProt | 20422042, 20553326, 14521924 | ||
| Y93 | Phosphorylation | P06241 (FYN) | score2 | neXtProt | 18691334 | |
| S222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y479 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S495 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S700 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T941 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S946 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S968 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S999 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1260 | Acetylation | score1 | PhosphoSitePlus | |||
| S1262 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S1340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1344 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1345 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S81 | F81 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| S222 | P222 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S700 | F700 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View