iPTMnet Report for Q6YP21 (KYAT3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6YP21 / KAT3_HUMAN
Protein Name Kynurenine--oxoglutarate transaminase 3
Gene Name Name: KYAT3
Synonyms:CCBL2,KAT3;
Organism Homo sapiens (Human)

PRO ID PR:Q6YP21
DAG View
PRO Name kynurenine--oxoglutarate transaminase 3 (human)
Definition A kynurenine--oxoglutarate transaminase 3 that is encoded in the genome of human.
Short Label hKYAT3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6YP21 (KYAT3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
F2 Acetylation UniProt 22814378
S12 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K38 Methylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
R99 Methylation PhosphoSitePlus
K108 Acetylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K116 Acetylation PhosphoSitePlus   UniProt 19608861
K120 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 Y22 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S76 F76 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K82 Q82 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K87 N87 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R99 Q99 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]