iPTMnet Report for Q6YN16 (HSDL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6YN16 / HSDL2_HUMAN
Protein Name Hydroxysteroid dehydrogenase-like protein 2
Gene Name Name: HSDL2
Synonyms:C9orf99,SDR13C1;
Organism Homo sapiens (Human)

PRO ID PR:Q6YN16
DAG View
PRO Name hydroxysteroid dehydrogenase-like protein 2 (human)
Definition A hydroxysteroid dehydrogenase-like protein 2 that is encoded in the genome of human.
Short Label hHSDL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6YN16 (HSDL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K29 Methylation PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
T53 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
K163 Methylation PhosphoSitePlus
K172 Methylation PhosphoSitePlus
C218 S-Nitrosylation dbSNO 26338901
K236 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S287 L287 Biomuta DOID:10534 / stomach cancer [ icgc ]
T288 S288 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K318 T318 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S320 C320 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]