iPTMnet Report for Q6YHK3 (CD109)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6YHK3 / CD109_HUMAN
Protein Name CD109 antigen precursor
Gene Name Name: CD109
Synonyms:CPAMD7;
Organism Homo sapiens (Human)

PRO ID PR:Q6YHK3
DAG View
PRO Name CD109 antigen (human)
Definition A CD109 molecule that is encoded in the genome of human.
Short Label hCD109
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6YHK3 (CD109) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
N41 N-Glycosylation GlyGen 23090970, 29741879, 24190977
C52 Methylation IEDB 31844290
N68 N-Glycosylation GlyGen   IEDB   UniProt 16335952, 24190977, 23090970, ...29391424, 19349973, 29741879, 27550523
Y102 Phosphorylation PhosphoSitePlus
N118 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 23090970, ...29391424, 19349973, 29741879
K143 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S173 Phosphorylation IEDB 35494241
N247 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 23090970, ...29391424, 16263699, 29741879
N279 N-Glycosylation GlyGen 23345538
N287 N-Glycosylation GlyGen 29741879, 29391424
N291 N-Glycosylation GlyGen 23090970, 24190977
N337 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
S339 O-Glycosylation GlyGen 34019948, 35289036
N397 N-Glycosylation GlyGen 23090970, 24190977
S403 O-Glycosylation GlyGen 34019948, 35289036
K417 Ubiquitination PhosphoSitePlus
N419 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 29391424, 29741879
Y446 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K491 Acetylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
N513 N-Glycosylation GlyGen 23090970, 23345538, 29391424, ...24190977
T581 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
Y660 Phosphorylation PhosphoSitePlus
T833 Phosphorylation PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
T946 Phosphorylation PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
K1022 Ubiquitination PhosphoSitePlus
S1036 Phosphorylation PhosphoSitePlus
N1086 N-Glycosylation GlyGen 23090970, 29391424, 24190977
Y1094 Phosphorylation IEDB 32387766
S1214 Phosphorylation PhosphoSitePlus
S1216 Phosphorylation PhosphoSitePlus
N1295 N-Glycosylation GlyGen 29391424
N1355 N-Glycosylation GlyGen 29741879, 23345538
Y1384 Phosphorylation PhosphoSitePlus
C1434 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
N279 N-Glycosylation PRO 23345538
Y467 Phosphorylation HPRD 20068231
N513 N-Glycosylation PRO 23345538
S579 Phosphorylation HPRD 20068231
T581 Phosphorylation HPRD 19413330
S585 Phosphorylation HPRD 19413330
N1355 N-Glycosylation PRO 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T31 I31 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K169 N169 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N279 K279 Biomuta DOID:1319 / brain cancer [ cosmic ]
N287 H287 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N419 T419 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y467 N467 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K491 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
N513 D513 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T840 I840 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K1022 Q1022 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]