iPTMnet Report for Q6XZF7 (DNMBP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6XZF7 / DNMBP_HUMAN
Protein Name Dynamin-binding protein
Gene Name Name: DNMBP
Synonyms:ARHGEF36;
Organism Homo sapiens (Human)

PRO ID PR:Q6XZF7
DAG View
PRO Name dynamin-binding protein (human)
Definition A dynamin-binding protein that is encoded in the genome of human.
Short Label hDNMBP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6XZF7 (DNMBP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T48 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
C120 Methylation IEDB 31844290
T275 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
T323 Phosphorylation phospho.ELM 18669648
S324 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
Y465 Phosphorylation PhosphoSitePlus
K469 Methylation PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
R480 Methylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus   UniProt 23186163
S504 Phosphorylation PhosphoSitePlus
Y505 Phosphorylation PhosphoSitePlus
K507 Methylation PhosphoSitePlus
K508 Methylation PhosphoSitePlus
T511 O-Glycosylation GlyGen 30379171, 35254053
T511 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
K675 Ubiquitination PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus   UniProt 23186163
T688 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
K891 Ubiquitination PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
T951 Phosphorylation PhosphoSitePlus
K971 Acetylation PhosphoSitePlus
K976 Methylation PhosphoSitePlus
K976 Ubiquitination PhosphoSitePlus
K979 Acetylation PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
K991 Acetylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S1005 Phosphorylation PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
K1019 Ubiquitination PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
C1056 Methylation IEDB 31844290
K1096 Ubiquitination PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
T1115 Phosphorylation PhosphoSitePlus
K1127 Ubiquitination PhosphoSitePlus
K1145 Ubiquitination PhosphoSitePlus
C1182 Methylation IEDB 31844290
C1191 Methylation IEDB 31844290
S1258 Phosphorylation PhosphoSitePlus
K1261 Ubiquitination PhosphoSitePlus
S1268 Phosphorylation PhosphoSitePlus
K1288 Ubiquitination PhosphoSitePlus
K1316 Methylation PhosphoSitePlus
K1317 Methylation PhosphoSitePlus
Y1339 Phosphorylation PhosphoSitePlus
S1353 Phosphorylation PhosphoSitePlus
T1363 Phosphorylation PhosphoSitePlus
S1371 Phosphorylation IEDB 27920218
S1379 Phosphorylation PhosphoSitePlus
S1407 Phosphorylation PhosphoSitePlus
S1436 Phosphorylation PhosphoSitePlus
T1460 Phosphorylation PhosphoSitePlus
T1462 Phosphorylation PhosphoSitePlus
Y1477 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus
Y1570 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T323 Phosphorylation HPRD 18669648
S495 Phosphorylation HPRD 20068231
S496 Phosphorylation HPRD 20068231
S659 Phosphorylation HPRD 15302935
S996 Phosphorylation HPRD 18491316
S1381 Phosphorylation HPRD 20068231
S1478 Phosphorylation HPRD 18707149


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S324 Y324 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S359 Y359 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T432 I432 Biomuta DOID:4159 / skin cancer [ cosmic ]
T453 N453 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y456 H456 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S483 Y483 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S485 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S495 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S504 N504 Biomuta DOID:4159 / skin cancer [ cosmic ]
T511 M511 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K572 N572 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K594 T594 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S659 F659 Biomuta DOID:4159 / skin cancer [ cosmic ]
S684 N684 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
Y708 H708 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K891 N891 Biomuta DOID:3571 / liver cancer [ cosmic ]
K988 N988 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S996 F996 Biomuta DOID:1319 / brain cancer [ icgc ]
K1127 N1127 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1407 Y1407 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T1460 I1460 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T1462 M1462 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1478 F1478 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]