Protein Information

Cytoscape View

UniProt AC / UniProt ID Q6XQN6 / PNCB_HUMAN
Protein Name Nicotinate phosphoribosyltransferase
Gene Name Name: NAPRT
Organism Homo sapiens (Human)

DAG View
PRO Name nicotinate phosphoribosyltransferase (human)
Definition A nicotinate phosphoribosyltransferase that is encoded in the genome of human.
Short Label hNAPRT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q6XQN6 (NAPRT) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
R405 Methylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus   UniProt 21406692, 16964243, 18669648, ...24275569, 20068231, 17081983
Site PTM Type PTM Enzyme Score Source PMID
S531 Phosphorylation HPRD 20068231
S537 Phosphorylation HPRD 16964243, 20230923, 18767875, ...19664995, 18669648, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R405 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T416 M416 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
K421 R421 Biomuta DOID:1909 / melanoma [ cosmic ]