iPTMnet Report Q6WN34 CHRDL2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q6WN34 / CRDL2_HUMAN
Protein Name	Chordin-like protein 2 precursor
Gene Name	Name: CHRDL2 Synonyms:BNF1,CHL2;ORFNames:UNQ765/PRO1557;
Organism	Homo sapiens (Human)

PRO ID	PR:Q6WN34 DAG View
PRO Name	chordin-like protein 2 (human)
Definition	A chordin-like protein 2 that is encoded in the genome of human.
Short Label	hCHRDL2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q6WN34 (CHRDL2) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T100	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	N114	N-Glycosylation		score2	GlyGen UniProt	32125861, 18780401
	S182	Phosphorylation		score2	PhosphoSitePlus UniProt	26091039
	T217	O-Glycosylation		score1	GlyGen	30459171
	T342	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	S343	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	S345	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	S345	Phosphorylation		score1	PhosphoSitePlus
	S347	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533
	S422	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S402	Phosphorylation		score0	HPRD	19824718

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S182	L182	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S343	L343	Biomuta		DOID:363 / uterine cancer [ icgc ]
S345	F345	Biomuta		DOID:4159 / skin cancer [ cosmic ]
S402	T402	Biomuta		DOID:2394 / ovarian cancer [ cosmic, icgc ]