iPTMnet Report for Q6UY14 (ADAMTSL4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UY14 / ATL4_HUMAN
Protein Name ADAMTS-like protein 4 precursor
Gene Name Name: ADAMTSL4
Synonyms:TSRC1;ORFNames:PP1396,UNQ2803/PRO34012;
Organism Homo sapiens (Human)

PRO ID PR:Q6UY14
DAG View
PRO Name ADAMTS-like protein 4 (human)
Definition An ADAMTS-like protein 4 that is encoded in the genome of human.
Short Label hADAMTSL4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UY14 (ADAMTSL4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T106 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S107 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
Y159 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S181 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S196 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
T223 O-Glycosylation GlyGen 30459171
S232 O-Glycosylation GlyGen 30459171
T235 O-Glycosylation GlyGen 30459171
T260 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S264 Phosphorylation PhosphoSitePlus
T266 O-Glycosylation GlyGen 30459171
S268 O-Glycosylation GlyGen 30459171
S291 O-Glycosylation GlyGen 30459171
S304 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T319 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S482 Phosphorylation PhosphoSitePlus
N490 N-Glycosylation GlyGen   UniProt 16335952, 19139490
T492 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
T576 Phosphorylation PhosphoSitePlus
T610 O-Glycosylation GlyGen 30459171
S696 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
N1001 N-Glycosylation GlyGen 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S107 I107 Biomuta DOID:4159 / skin cancer [ cosmic ]
S177 T177 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S181 Y181 Biomuta DOID:363 / uterine cancer [ icgc ]
T223 N223 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T223 A223 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T266 M266 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S304 W304 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T319 A319 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S571 P571 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S696 L696 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S796 F796 Biomuta DOID:4606 / bile duct cancer [ cosmic ]