iPTMnet Report for Q6UXM1 (LRIG3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UXM1 / LRIG3_HUMAN
Protein Name Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor
Gene Name Name: LRIG3
Synonyms:LIG3;ORFNames:UNQ287/PRO326/PRO335;
Organism Homo sapiens (Human)

PRO ID PR:Q6UXM1
DAG View
PRO Name leucine-rich repeats and immunoglobulin-like domains protein 3 (human)
Definition A leucine-rich repeats and immunoglobulin-like domains protein 3 that is encoded in the genome of human.
Short Label hLRIG3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UXM1 (LRIG3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S372 Phosphorylation PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
T598 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
T731 Phosphorylation PhosphoSitePlus
Y936 Phosphorylation PhosphoSitePlus
S949 Phosphorylation PhosphoSitePlus
S984 Phosphorylation PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
K996 Ubiquitination PhosphoSitePlus
S1001 Phosphorylation PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
S1030 Phosphorylation PhosphoSitePlus
Y1053 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
S1079 Phosphorylation PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus
K1101 Ubiquitination PhosphoSitePlus
S1114 Phosphorylation PhosphoSitePlus
Y1115 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S372 F372 Biomuta DOID:4159 / skin cancer [ cosmic ]
S984 N984 Biomuta DOID:363 / uterine cancer [ icgc ]
S989 L989 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K996 N996 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1018 F1018 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S1030 L1030 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
Y1053 C1053 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1073 Y1073 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1114 T1114 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]