iPTMnet Report for Q6UXH1 (CRELD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UXH1 / CREL2_HUMAN
Protein Name Protein disulfide isomerase CRELD2 precursor
Gene Name Name: CRELD2
ORFNames:UNQ185/PRO211;
Organism Homo sapiens (Human)

PRO ID PR:Q6UXH1
DAG View
PRO Name protein disulfide isomerase CRELD2 (human)
Definition A protein disulfide isomerase CRELD2 that is encoded in the genome of human.
Short Label hCRELD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UXH1 (CRELD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
T58 O-Glycosylation GlyGen   PhosphoSitePlus 25813380
K63 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
N190 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S202 O-Glycosylation GlyGen 22661428
N251 N-Glycosylation GlyGen 29741879
K275 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T229 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T58 M58 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K63 N63 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S187 L187 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T229 M229 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]