iPTMnet Report for Q6UX71 (PLXDC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UX71 / PXDC2_HUMAN
Protein Name Plexin domain-containing protein 2 precursor
Gene Name Name: PLXDC2
Synonyms:TEM7R;ORFNames:UNQ2514/PRO6003;
Organism Homo sapiens (Human)

PRO ID PR:Q6UX71
DAG View
PRO Name plexin domain-containing protein 2 (human)
Definition A plexin domain-containing protein 2 that is encoded in the genome of human.
Short Label hPLXDC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UX71 (PLXDC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S86 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S86 Phosphorylation PhosphoSitePlus
N103 N-Glycosylation GlyGen   UniProt 16335952
S150 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
N160 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N316 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N345 N-Glycosylation GlyGen 29741879
T395 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
T419 O-Glycosylation GlyGen 30459171
T419 Phosphorylation PhosphoSitePlus
T427 O-Glycosylation GlyGen 30459171
S495 Phosphorylation PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y511 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S506 Phosphorylation HPRD 19651622, 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S86 F86 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ]
T152 I152 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
N345 K345 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T395 I395 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T400 S400 Biomuta DOID:1324 / lung cancer [ cosmic ]
T414 N414 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S506 P506 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S506 Y506 Biomuta DOID:4159 / skin cancer [ cosmic ]