iPTMnet Report for Q6UX04 (CWC27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UX04 / CWC27_HUMAN
Protein Name Spliceosome-associated protein CWC27 homolog
Gene Name Name: CWC27
Synonyms:SDCCAG10;ORFNames:UNQ438/PRO871;
Organism Homo sapiens (Human)

PRO ID PR:Q6UX04
DAG View
PRO Name spliceosome-associated protein CWC27 homolog (human)
Definition A spliceosome-associated protein CWC27 homolog that is encoded in the genome of human.
Short Label hCWC27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UX04 (CWC27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
K31 Ubiquitination PhosphoSitePlus
R119 Methylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
N201 N-Glycosylation GlyGen   UniProt 16335952
S203 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
K237 Sumoylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K372 Methylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
Y447 Phosphorylation PhosphoSitePlus
K462 Acetylation PhosphoSitePlus
K468 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T293 Phosphorylation HPRD 17924679
S294 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 I31 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K31 E31 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R119 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R119 G119 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K192 N192 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S203 R203 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S224 N224 Biomuta DOID:9256 / colorectal cancer [ cosmic ]