iPTMnet Report for Q6UWZ7 (ABRAXAS1)
Protein Information
UniProt AC / UniProt ID | Q6UWZ7 / ABRX1_HUMAN |
Protein Name | BRCA1-A complex subunit Abraxas 1 |
Gene Name | Name: ABRAXAS1 Synonyms:ABRA1;ORFNames:UNQ496/PRO1013; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6UWZ7 |
PRO Name | BRCA1-A complex subunit Abraxas 1 (human) |
Definition | A BRCA1-A complex subunit Abraxas 1 that is encoded in the genome of human. |
Short Label | hABRAXAS1 |
Category | organism-gene |
Q6UWZ7 (ABRAXAS1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
K242 | Ubiquitination | score1 | PhosphoSitePlus | |||
K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
R285 | Methylation | score1 | PhosphoSitePlus | |||
K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
T340 | Phosphorylation | score1 | PhosphoSitePlus | |||
K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
K358 | Methylation | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
T365 | Phosphorylation | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
S386 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 20068231 | ||
S387 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 20068231 | ||
T390 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
K396 | Ubiquitination | score1 | PhosphoSitePlus | |||
K398 | Sumoylation | score1 | PhosphoSitePlus | |||
K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
S404 | Phosphorylation | Q13315 (ATM) | score3 | PhosphoSitePlus Signor UniProt | 26778126 | |
S406 | Phosphorylation | Q13315 (ATM) | score4 | phospho.ELM PRO PhosphoSitePlus Signor UniProt | 23186163, 18669648, 17525340, ... | |
T408 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T365 | Phosphorylation | score0 | HPRD | 17525332 | ||
S383 | Phosphorylation | score0 | HPRD | 18669648 | ||
S386 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S387 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
T390 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S406 | Phosphorylation | score2 | HPRD | 19413330, 18767875, 20058876, ... | ||
T408 | Phosphorylation | score0 | HPRD | 20068231 |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000047364 (hABRAXAS1/Phos:1) | pS406 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S48 | F48 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] | |
S90 | L90 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K93 | N93 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K201 | N201 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K268 | N268 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
R285 | W285 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] | |
K302 | Q302 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K384 | T384 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K396 | N396 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |