iPTMnet Report for Q6UWP7 (LCLAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UWP7 / LCLT1_HUMAN
Protein Name Lysocardiolipin acyltransferase 1
Gene Name Name: LCLAT1
Synonyms:AGPAT8;ORFNames:UNQ1849/PRO3579;
Organism Homo sapiens (Human)

PRO ID PR:Q6UWP7
DAG View
PRO Name lysocardiolipin acyltransferase 1 (human)
Definition A lysocardiolipin acyltransferase 1 that is encoded in the genome of human.
Short Label hLCLAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UWP7 (LCLAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y77 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K221 Acetylation PhosphoSitePlus   UniProt 19608861
K221 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
R244 Methylation PhosphoSitePlus
R246 Methylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K306 Sumoylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
C336 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R244 C244 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R244 H244 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K297 E297 Biomuta DOID:10534 / stomach cancer [ cosmic ]