iPTMnet Report for Q6UWJ1 (TMCO3)
Protein Information
| UniProt AC / UniProt ID | Q6UWJ1 / TMCO3_HUMAN |
| Protein Name | Transmembrane and coiled-coil domain-containing protein 3 precursor |
| Gene Name | Name: TMCO3 Synonyms:C13orf11;ORFNames:UNQ2419/PRO4976; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6UWJ1 |
| PRO Name | transmembrane and coiled-coil domain-containing protein 3 (human) |
| Definition | A transmembrane and coiled-coil domain-containing protein 3 that is encoded in the genome of human. |
| Short Label | hTMCO3 |
| Category | organism-gene |
Q6UWJ1 (TMCO3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T151 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| Y153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S176 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S208 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S227 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N230 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K257 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K64 | N64 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K207 | T207 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S208 | L208 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View