Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UWE0 / LRSM1_HUMAN
Protein Name E3 ubiquitin-protein ligase LRSAM1
Gene Name Name: LRSAM1
Synonyms:TAL;ORFNames:UNQ6496/PRO21356;
Organism Homo sapiens (Human)

PRO ID PR:Q6UWE0
DAG View
PRO Name E3 ubiquitin-protein ligase LRSAM1 (human)
Definition An E3 ubiquitin-protein ligase LRSAM1 that is encoded in the genome of human.
Short Label hLRSAM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UWE0 (LRSAM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y187 Phosphorylation PhosphoSitePlus
Y218 Phosphorylation PhosphoSitePlus
S234 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y256 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S604 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S234 Phosphorylation HPRD 18669648
S601 Phosphorylation HPRD 20068231
S604 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S289 I289 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T298 M298 Biomuta DOID:363 / uterine cancer [ tcga ]
S337 I337 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
S494 P494 Biomuta DOID:10534 / stomach cancer [ tcga ]
S604 T604 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]