iPTMnet Report for Q6UW60 (PCSK4)
Protein Information
| UniProt AC / UniProt ID | Q6UW60 / PCSK4_HUMAN |
| Protein Name | Proprotein convertase subtilisin/kexin type 4 precursor |
| Gene Name | Name: PCSK4 Synonyms:PC4;ORFNames:UNQ2757/PRO6496; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6UW60 |
| PRO Name | proprotein convertase subtilisin/kexin type 4 (human) |
| Definition | A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of human. |
| Short Label | hPCSK4 |
| Category | organism-gene |
DAG ViewQ6UW60 (PCSK4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T635 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T641 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S650 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S651 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S655 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S258 | C258 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S655 | F655 | Biomuta | DOID:4159 / skin cancer [ icgc ] |
