Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ULP2 / AFTIN_HUMAN
Protein Name Aftiphilin
Gene Name Name: AFTPH
Synonyms:AFTH;
Organism Homo sapiens (Human)

PRO ID PR:Q6ULP2
DAG View
PRO Name aftiphilin (human)
Definition An aftiphilin that is encoded in the genome of human.
Short Label hAFTPH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ULP2 (AFTPH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y52 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S226 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
K357 Acetylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S382 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S387 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
C511 S-Nitrosylation dbSNO 26338901
S517 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus   UniProt 24275569
T520 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus
T617 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 19690332
K687 Ubiquitination PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
Y753 Phosphorylation PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
T925 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation HPRD 20068231
S382 Phosphorylation HPRD 15302935
S411 Phosphorylation HPRD 19651622, 20068231
S517 Phosphorylation HPRD 19007248
T522 Phosphorylation HPRD 19007248
T617 Phosphorylation HPRD 16964243
S729 Phosphorylation HPRD 20068231
S730 Phosphorylation HPRD 20068231
T735 Phosphorylation HPRD 20068231
T763 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation HPRD 20068231
S382 Phosphorylation HPRD 15302935
S411 Phosphorylation HPRD 19651622, 20068231
S517 Phosphorylation HPRD 19007248
T522 Phosphorylation HPRD 19007248
T617 Phosphorylation HPRD 16964243
S729 Phosphorylation HPRD 20068231
S730 Phosphorylation HPRD 20068231
T735 Phosphorylation HPRD 20068231
T763 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation HPRD 20068231
S382 Phosphorylation HPRD 15302935
S411 Phosphorylation HPRD 19651622, 20068231
S517 Phosphorylation HPRD 19007248
T522 Phosphorylation HPRD 19007248
T617 Phosphorylation HPRD 16964243
S729 Phosphorylation HPRD 20068231
S730 Phosphorylation HPRD 20068231
T735 Phosphorylation HPRD 20068231
T763 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R130 I130 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S275 F275 Biomuta DOID:363 / uterine cancer [ tcga ]
S387 I387 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S409 F409 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
C511 Y511 Biomuta DOID:3571 / liver cancer [ icgc ]
S518 I518 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T617 I617 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
Y753 H753 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S930 R930 Biomuta DOID:1612 / breast cancer [ tcga ]