iPTMnet Report for Q6TFL4 (KLHL24)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6TFL4 / KLH24_HUMAN
Protein Name Kelch-like protein 24
Gene Name Name: KLHL24
Synonyms:DRE1;
Organism Homo sapiens (Human)

PRO ID PR:Q6TFL4
DAG View
PRO Name kelch-like protein 24 (human)
Definition A kelch-like protein 24 that is encoded in the genome of human.
Short Label hKLHL24
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6TFL4 (KLHL24) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
C71 Methylation IEDB 31844290
K181 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
C321 Methylation IEDB 31844290
K347 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
C587 Methylation IEDB 31844290
K596 Ubiquitination PhosphoSitePlus
C597 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S19 F19 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
K25 T25 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K186 T186 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K492 R492 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S499 F499 Biomuta DOID:4159 / skin cancer [ cosmic ]
C597 R597 Biomuta DOID:363 / uterine cancer [ icgc ]