iPTMnet Report for Q6SJ93 (FAM111B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6SJ93 / F111B_HUMAN
Protein Name Serine protease FAM111B
Gene Name Name: FAM111B
Synonyms:CANP;
Organism Homo sapiens (Human)

PRO ID PR:Q6SJ93
DAG View
PRO Name serine protease FAM111B (human)
Definition A serine protease FAM111B that is encoded in the genome of human.
Short Label hFAM111B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6SJ93 (FAM111B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S3 Phosphorylation PhosphoSitePlus
K5 Sumoylation PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
C43 Methylation IEDB 31844290
K49 Ubiquitination PhosphoSitePlus
T53 Phosphorylation PhosphoSitePlus
K55 Methylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
C226 Methylation IEDB 31844290
K227 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K270 Methylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
Y402 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
C451 Methylation IEDB 31844290
C488 Methylation IEDB 31844290
Y545 Phosphorylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
Y702 Phosphorylation PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
Y713 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 C3 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S3 F3 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K5 N5 Biomuta DOID:1324 / lung cancer [ cosmic ]
T6 N6 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y100 C100 Biomuta DOID:4159 / skin cancer [ cosmic ]
K122 N122 Biomuta DOID:1324 / lung cancer [ cosmic ]
K241 T241 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y349 C349 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y402 S402 Biomuta DOID:1324 / lung cancer [ cosmic ]
S426 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C488 S488 Biomuta DOID:9256 / colorectal cancer [ cosmic ]