Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6RI45 / BRWD3_HUMAN
Protein Name Bromodomain and WD repeat-containing protein 3
Gene Name Name: BRWD3
Organism Homo sapiens (Human)

PRO ID PR:Q6RI45
DAG View
PRO Name bromodomain and WD repeat-containing protein 3 (human)
Definition A bromodomain and WD repeat-containing protein 3 that is encoded in the genome of human.
Short Label hBRWD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6RI45 (BRWD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus   UniProt 23186163
S702 Phosphorylation PhosphoSitePlus
S703 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 20068231
S885 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
Y948 Phosphorylation PhosphoSitePlus
K964 Ubiquitination PhosphoSitePlus
K987 Ubiquitination PhosphoSitePlus
Y1024 Phosphorylation PhosphoSitePlus
Y1040 Phosphorylation PhosphoSitePlus
T1235 Phosphorylation PhosphoSitePlus
K1256 Ubiquitination PhosphoSitePlus
S1264 Phosphorylation PhosphoSitePlus
T1265 Phosphorylation PhosphoSitePlus
T1271 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
K1402 Methylation PhosphoSitePlus
Y1404 Phosphorylation PhosphoSitePlus
T1405 Phosphorylation PhosphoSitePlus
S1406 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
Y1413 Phosphorylation PhosphoSitePlus
K1450 Ubiquitination PhosphoSitePlus
S1455 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S1466 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T1569 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1577 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1579 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1599 Phosphorylation PhosphoSitePlus
T1603 Phosphorylation PhosphoSitePlus
S1606 Phosphorylation PhosphoSitePlus
S1611 Phosphorylation PhosphoSitePlus
S1612 Phosphorylation PhosphoSitePlus
R1740 Methylation PhosphoSitePlus
R1743 Methylation PhosphoSitePlus
S1763 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T268 N268 Biomuta DOID:3571 / liver cancer [ icgc ]
S337 T337 Biomuta DOID:1612 / breast cancer [ cosmic ]
S685 R685 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K964 E964 Biomuta DOID:10534 / stomach cancer [ tcga ]
T1265 A1265 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T1405 N1405 Biomuta DOID:3571 / liver cancer [ icgc ]
S1410 * Biomuta DOID:1909 / melanoma [ tcga ]
K1450 T1450 Biomuta DOID:0070003 / blastoma [ cosmic ]
S1455 I1455 Biomuta DOID:1324 / lung cancer [ tcga ]
S1455 N1455 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1466 G1466 Biomuta DOID:3070 / malignant glioma [ tcga ]
S1577 G1577 Biomuta DOID:363 / uterine cancer [ tcga ]
S1611 F1611 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R1740 C1740 Biomuta DOID:1909 / melanoma [ cosmic ]
R1743 K1743 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]