iPTMnet Report for Q6R6M4 (USP17L2)
Protein Information
| UniProt AC / UniProt ID | Q6R6M4 / U17L2_HUMAN |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 17 |
| Gene Name | Name: USP17L2 Synonyms:DUB3,USP17,USP17H,USP17I,USP17J,USP17K,USP17L,USP17M; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6R6M4 |
| PRO Name | ubiquitin carboxyl-terminal hydrolase 17 (human) |
| Definition | A ubiquitin carboxyl-terminal hydrolase 17 that is encoded in the genome of human. |
| Short Label | hUSP17L2 |
| Category | organism-gene |
Q6R6M4 (USP17L2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S41 | Phosphorylation | score0 | RLIMS-P | 28067227 | ||
| S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T360 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y368 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T399 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S41 | L41 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| T287 | S287 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S361 | Y361 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View