iPTMnet Report for Q6Q759 (SPAG17)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6Q759 / SPG17_HUMAN
Protein Name Sperm-associated antigen 17
Gene Name Name: SPAG17
Organism Homo sapiens (Human)

PRO ID PR:Q6Q759
DAG View
PRO Name sperm-associated antigen 17 (human)
Definition A sperm-associated antigen 17 that is encoded in the genome of human.
Short Label hSPAG17
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6Q759 (SPAG17) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K159 Acetylation PhosphoSitePlus
K161 Acetylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K171 Acetylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
K404 Methylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
K957 Methylation PhosphoSitePlus
K962 Methylation PhosphoSitePlus
K968 Acetylation PhosphoSitePlus
K969 Acetylation PhosphoSitePlus
K970 Acetylation PhosphoSitePlus
S987 Phosphorylation PhosphoSitePlus
K992 Acetylation PhosphoSitePlus
S1121 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation HPRD   PhosphoSitePlus 20058876
S1139 Phosphorylation HPRD   PhosphoSitePlus 20058876
T1153 Phosphorylation PhosphoSitePlus
T1171 Phosphorylation PhosphoSitePlus
S1175 Phosphorylation PhosphoSitePlus
T1352 Phosphorylation PhosphoSitePlus
T1354 Phosphorylation PhosphoSitePlus
T1433 Phosphorylation HPRD 17081983
S1751 Phosphorylation PhosphoSitePlus
S1826 Phosphorylation PhosphoSitePlus
S1836 Phosphorylation PhosphoSitePlus
T1839 Phosphorylation PhosphoSitePlus
T1846 Phosphorylation PhosphoSitePlus
S1852 Phosphorylation PhosphoSitePlus
Y1899 Phosphorylation PhosphoSitePlus
S1969 O-Glycosylation GlyGen 30379171
S1981 Phosphorylation PhosphoSitePlus
T1997 Phosphorylation PhosphoSitePlus
T2058 Phosphorylation PhosphoSitePlus
Y2208 Phosphorylation PhosphoSitePlus
S2209 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S66 N66 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K171 R171 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T880 N880 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S888 T888 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S888 Y888 Biomuta DOID:363 / uterine cancer [ icgc ]
K957 T957 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K957 N957 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K962 T962 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S987 L987 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1121 Y1121 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1139 L1139 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1175 R1175 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1846 I1846 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1981 F1981 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1981 Y1981 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1997 A1997 Biomuta DOID:9256 / colorectal cancer [ cosmic ]