iPTMnet Report for Q6PL18 (ATAD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PL18 / ATAD2_HUMAN
Protein Name ATPase family AAA domain-containing protein 2
Gene Name Name: ATAD2
ORFNames:L16,PRO2000;
Organism Homo sapiens (Human)

PRO ID PR:Q6PL18
DAG View
PRO Name ATPase family AAA domain-containing protein 2 (human)
Definition An ATPase family AAA domain-containing protein 2 that is encoded in the genome of human.
Short Label hATAD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PL18 (ATAD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation IEDB   PhosphoSitePlus 32897882
K48 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus   UniProt 23186163
S61 Phosphorylation PhosphoSitePlus   UniProt 23186163
K63 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus   UniProt 23186163
S170 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K175 Acetylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
S327 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S336 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S337 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S342 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
Y344 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus   UniProt 23186163
S421 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
K497 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
C649 Methylation IEDB 31844290
S670 Phosphorylation PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
S696 Phosphorylation IEDB 32387766
K706 Ubiquitination PhosphoSitePlus
S746 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y750 Phosphorylation PhosphoSitePlus
S751 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935
S757 Phosphorylation PhosphoSitePlus
K772 Acetylation PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
T852 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
Y858 Phosphorylation PhosphoSitePlus
K926 Ubiquitination PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
S969 Phosphorylation PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
K976 Ubiquitination PhosphoSitePlus
T997 Phosphorylation PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
K1026 Ubiquitination PhosphoSitePlus
K1037 Ubiquitination PhosphoSitePlus
K1042 Ubiquitination PhosphoSitePlus
Y1043 Phosphorylation PhosphoSitePlus
K1047 Ubiquitination PhosphoSitePlus
Y1049 Phosphorylation PhosphoSitePlus
Y1063 Phosphorylation PhosphoSitePlus
T1084 Phosphorylation PhosphoSitePlus
Y1086 Phosphorylation PhosphoSitePlus
K1090 Sumoylation PhosphoSitePlus
K1117 Ubiquitination PhosphoSitePlus
Y1122 Phosphorylation PhosphoSitePlus
K1128 Ubiquitination PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
T1132 Phosphorylation PhosphoSitePlus
K1137 Ubiquitination PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1146 Ubiquitination PhosphoSitePlus
K1148 Ubiquitination PhosphoSitePlus
T1149 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1151 Phosphorylation PhosphoSitePlus
T1152 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1157 Phosphorylation PhosphoSitePlus
T1158 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1163 Ubiquitination PhosphoSitePlus
S1170 Phosphorylation PhosphoSitePlus
T1176 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1184 Phosphorylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S1233 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1235 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1236 Ubiquitination PhosphoSitePlus
S1243 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T1245 Phosphorylation PhosphoSitePlus
S1255 Phosphorylation PhosphoSitePlus
K1257 Ubiquitination PhosphoSitePlus
T1258 Phosphorylation PhosphoSitePlus
T1259 Phosphorylation PhosphoSitePlus
T1262 Phosphorylation PhosphoSitePlus
K1267 Ubiquitination PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation PhosphoSitePlus
S1277 Phosphorylation PhosphoSitePlus
S1283 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
K1314 Ubiquitination PhosphoSitePlus
T1323 Phosphorylation PhosphoSitePlus   UniProt 23186163
C1362 Methylation IEDB 31844290
K1372 Ubiquitination PhosphoSitePlus
K1378 Ubiquitination PhosphoSitePlus
C1388 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation HPRD 20068231
S132 Phosphorylation HPRD 17924679
Y322 Phosphorylation HPRD 19651622, 17081983
S323 Phosphorylation HPRD 19651622, 17081983
S327 Phosphorylation HPRD 19651622, 17081983, 20068231
S336 Phosphorylation HPRD 18669648, 20068231
S337 Phosphorylation HPRD 19664995, 20068231
S342 Phosphorylation HPRD 18669648, 17081983, 20068231, ...19664995
S670 Phosphorylation HPRD 20068231
T695 Phosphorylation HPRD 20068231
S746 Phosphorylation HPRD 18669648
S751 Phosphorylation HPRD 18669648, 15302935, 20068231
T971 Phosphorylation HPRD 19691289
T1084 Phosphorylation HPRD 20068231
Y1086 Phosphorylation HPRD 20068231
T1149 Phosphorylation HPRD 18669648
T1152 Phosphorylation HPRD 18669648
T1158 Phosphorylation HPRD 19413330, 18669648
S1200 Phosphorylation HPRD 20068231, 18452278
S1233 Phosphorylation HPRD 20068231
S1243 Phosphorylation HPRD 19413330, 17081983, 20068231
S1302 Phosphorylation HPRD 18669648, 19007248, 19691289, ...20068231, 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S41 L41 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S76 F76 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S84 Y84 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T211 P211 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K311 Q311 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K311 I311 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y322 C322 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S336 T336 Biomuta DOID:1324 / lung cancer [ cosmic ]
S336 F336 Biomuta DOID:4159 / skin cancer [ cosmic ]
S360 L360 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
K406 N406 Biomuta DOID:1324 / lung cancer [ cosmic ]
K456 E456 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T695 P695 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T852 R852 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K931 T931 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K931 N931 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K931 R931 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K950 R950 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S969 L969 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1011 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K1026 E1026 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y1049 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S1139 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1157 N1157 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1184 L1184 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1200 G1200 Biomuta DOID:363 / uterine cancer [ icgc ]
S1233 F1233 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1243 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S1275 Y1275 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1275 T1275 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S1276 G1276 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1283 Y1283 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]