iPTMnet Report for Q6PKC3 (TXNDC11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PKC3 / TXD11_HUMAN
Protein Name Thioredoxin domain-containing protein 11
Gene Name Name: TXNDC11
Synonyms:EFP1;
Organism Homo sapiens (Human)

PRO ID PR:Q6PKC3
DAG View
PRO Name thioredoxin domain-containing protein 11 (human)
Definition A thioredoxin domain-containing protein 11 that is encoded in the genome of human.
Short Label hTXNDC11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PKC3 (TXNDC11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C67 Methylation IEDB 31844290
S99 O-Glycosylation GlyGen   IEDB 28314751
Y120 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
S316 Phosphorylation IEDB   PhosphoSitePlus 27869121
N326 N-Glycosylation GlyGen 24190977
N337 N-Glycosylation GlyGen 24190977
C344 Methylation IEDB 31844290
T558 O-Glycosylation GlyGen 30459171
K566 Ubiquitination PhosphoSitePlus
N595 N-Glycosylation GlyGen 29741879
K675 Ubiquitination PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
K813 Ubiquitination PhosphoSitePlus
S828 Phosphorylation UniProt 17693683
Site PTM Type PTM Enzyme Score Source PMID
S801 Phosphorylation HPRD 17693683


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S316 P316 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T558 I558 Biomuta DOID:1324 / lung cancer [ cosmic ]
N595 A595 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S776 R776 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S801 F801 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K813 N813 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S828 F828 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]