iPTMnet Report for Q6PJG6 (BRAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PJG6 / BRAT1_HUMAN
Protein Name BRCA1-associated ATM activator 1
Gene Name Name: BRAT1
Synonyms:BAAT1,C7orf27;
Organism Homo sapiens (Human)

PRO ID PR:Q6PJG6
DAG View
PRO Name BRCA1-associated ATM activator 1 (human)
Definition A BRCA1-associated ATM activator 1 that is encoded in the genome of human.
Short Label hBRAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PJG6 (BRAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Ubiquitination PhosphoSitePlus
C54 Methylation IEDB 31844290
C89 Methylation IEDB 31844290
S121 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
C487 Methylation IEDB 31844290
K507 Ubiquitination PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
T671 Phosphorylation PhosphoSitePlus
Y675 Phosphorylation PhosphoSitePlus
C720 Methylation IEDB 31844290
K729 Ubiquitination PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S742 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18669648, 20068231
T745 Phosphorylation PhosphoSitePlus
T751 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
K797 Ubiquitination PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C89 F89 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S121 R121 Biomuta DOID:3571 / liver cancer [ cosmic ]
K304 Q304 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
K358 E358 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K358 N358 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S519 A519 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S742 I742 Biomuta DOID:2531 / hematologic cancer [ cosmic ]