iPTMnet Report for Q6PJ69 (TRIM65)
Protein Information
| UniProt AC / UniProt ID | Q6PJ69 / TRI65_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase TRIM65 |
| Gene Name | Name: TRIM65 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6PJ69 |
| PRO Name | tripartite motif-containing protein 65 (human) |
| Definition | A tripartite motif-containing protein 65 that is encoded in the genome of human. |
| Short Label | hTRIM65 |
| Category | organism-gene |
DAG ViewQ6PJ69 (TRIM65) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22223895 | ||
| S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S167 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31332286 | ||
| S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R342 | Methylation | score1 | PhosphoSitePlus | |||
| S367 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31332286 | ||
| T413 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31332286 | ||
| C426 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S172 | L172 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| R342 | C342 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| C426 | Y426 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
