iPTMnet Report for Q6PIY7 (TENT2)
Protein Information
UniProt AC / UniProt ID | Q6PIY7 / GLD2_HUMAN |
Protein Name | Poly(A) RNA polymerase GLD2 |
Gene Name | Name: TENT2 Synonyms:GLD2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6PIY7 |
PRO Name | poly(A) RNA polymerase GLD2 (human) |
Definition | A poly(A) RNA polymerase GLD2 that is encoded in the genome of human. |
Short Label | hTENT2 |
Category | organism-gene |
Q6PIY7 (TENT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S69 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
R73 | Methylation | score1 | PhosphoSitePlus | |||
R75 | Methylation | score1 | PhosphoSitePlus | |||
K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
R90 | Methylation | score1 | PhosphoSitePlus | |||
R92 | Methylation | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | P31749 (AKT1) , P17612 (PRKACA) , P22694 (PRKACB) , P22612 (PRKACG) | score3 | PhosphoSitePlus Signor | 31057087 | |
R131 | Methylation | score1 | PhosphoSitePlus | |||
C132 | Methylation | score1 | IEDB | 31844290 | ||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y253 | Phosphorylation | score1 | PhosphoSitePlus | |||
K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
R325 | Methylation | score1 | PhosphoSitePlus | |||
K428 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y429 | Phosphorylation | score1 | PhosphoSitePlus | |||
T439 | Phosphorylation | score1 | PhosphoSitePlus | |||
T441 | Phosphorylation | score1 | PhosphoSitePlus | |||
K455 | Ubiquitination | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S69 | F69 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R73 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
R73 | L73 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R90 | W90 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R90 | Q90 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R92 | H92 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
R92 | C92 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
K175 | N175 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K175 | T175 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R325 | S325 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R325 | H325 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R325 | L325 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T439 | P439 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
K455 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |