iPTMnet Report for Q6PIU2 (NCEH1)
Protein Information
UniProt AC / UniProt ID | Q6PIU2 / NCEH1_HUMAN |
Protein Name | Neutral cholesterol ester hydrolase 1 |
Gene Name | Name: NCEH1 Synonyms:AADACL1,KIAA1363; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6PIU2 |
PRO Name | neutral cholesterol ester hydrolase 1 (human) |
Definition | A neutral cholesterol ester hydrolase 1 that is encoded in the genome of human. |
Short Label | hNCEH1 |
Category | organism-gene |
Q6PIU2 (NCEH1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y168 | Phosphorylation | score1 | PhosphoSitePlus | |||
T240 | Phosphorylation | score1 | PhosphoSitePlus | |||
N270 | N-Glycosylation | score3 | GlyGen | 29741879, 19592704 | ||
N287 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
T289 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 34019948, ... | ||
S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
T297 | Phosphorylation | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
N389 | N-Glycosylation | score2 | GlyGen | 19592704 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T85 | R85 | Biomuta | DOID:1324 / lung cancer [ icgc ] | |
S144 | F144 | Biomuta | DOID:1115 / sarcoma [ icgc ] | |
T240 | N240 | Biomuta | DOID:363 / uterine cancer [ icgc ] |