iPTMnet Report for Q6PHR2 (ULK3)
Protein Information
| UniProt AC / UniProt ID | Q6PHR2 / ULK3_HUMAN |
| Protein Name | Serine/threonine-protein kinase ULK3 |
| Gene Name | Name: ULK3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6PHR2 |
| PRO Name | serine/threonine-protein kinase ULK3 (human) |
| Definition | A serine/threonine-protein kinase ULK3 that is encoded in the genome of human. |
| Short Label | hULK3 |
| Category | organism-gene |
DAG ViewQ6PHR2 (ULK3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R10 | Methylation | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S165 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S176 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
| S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S300 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | ||
| S300 | Phosphorylation | Q6PHR2 (ULK3) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| S305 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K333 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S350 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | ||
| S350 | Phosphorylation | Q6PHR2 (ULK3) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | ||
| S384 | Phosphorylation | Q6PHR2 (ULK3) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S449 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K458 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S464 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | ||
| S464 | Phosphorylation | Q6PHR2 (ULK3) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K441 | Ubiquitination | score1 | PhosphoSitePlus |
Q6PHR2 (ULK3) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| Q6PHR2 (ULK3) | S300 | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| Q6PHR2 (ULK3) | S350 | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| Q6PHR2 (ULK3) | S384 | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 | |
| Q6PHR2 (ULK3) | S464 | score4 | neXtProt PhosphoSitePlus Signor UniProt | 19878745, 20643644 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S165 | F165 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S219 | L219 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| K333 | M333 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S449 | Y449 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
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