iPTMnet Report for Q6PGP7 (SKIC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PGP7 / SKI3_HUMAN
Protein Name Superkiller complex protein 3
Gene Name Name: SKIC3
Synonyms:KIAA0372;
Organism Homo sapiens (Human)

PRO ID PR:Q6PGP7
DAG View
PRO Name SKI3 subunit of superkiller complex protein (human)
Definition A SKI3 subunit of superkiller complex protein that is encoded in the genome of human.
Short Label hSKIC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PGP7 (SKIC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
K65 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
T145 Phosphorylation IEDB 35494241
K214 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
C442 Methylation IEDB 31844290
Y458 Phosphorylation PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
K484 Methylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K596 Ubiquitination PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
Y648 Phosphorylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
C849 Methylation IEDB 31844290
Y972 Phosphorylation PhosphoSitePlus
Y979 Phosphorylation PhosphoSitePlus
Y988 Phosphorylation PhosphoSitePlus
K997 Ubiquitination PhosphoSitePlus
K1038 Ubiquitination PhosphoSitePlus
K1068 Ubiquitination PhosphoSitePlus
K1087 Ubiquitination PhosphoSitePlus
T1104 Phosphorylation PhosphoSitePlus
K1108 Ubiquitination PhosphoSitePlus
T1139 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
Y1169 Phosphorylation PhosphoSitePlus
K1180 Ubiquitination PhosphoSitePlus
K1230 Ubiquitination PhosphoSitePlus
K1231 Ubiquitination PhosphoSitePlus
T1254 Phosphorylation PhosphoSitePlus
K1257 Ubiquitination PhosphoSitePlus
S1328 Phosphorylation PhosphoSitePlus
S1330 Phosphorylation PhosphoSitePlus
T1334 Phosphorylation PhosphoSitePlus
T1339 Phosphorylation PhosphoSitePlus
K1351 Ubiquitination PhosphoSitePlus
K1354 Ubiquitination PhosphoSitePlus
K1372 Ubiquitination PhosphoSitePlus
K1379 Ubiquitination PhosphoSitePlus
S1437 Phosphorylation PhosphoSitePlus
K1516 Ubiquitination PhosphoSitePlus
K1547 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K93 N93 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K112 T112 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K334 N334 Biomuta DOID:1324 / lung cancer [ cosmic ]
K392 E392 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y396 N396 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S401 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K434 N434 Biomuta DOID:1319 / brain cancer [ icgc ]
K484 N484 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K619 N619 Biomuta [ cosmic ]
K619 T619 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1328 Y1328 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1328 P1328 Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]