Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PGN9 / PSRC1_HUMAN
Protein Name Proline/serine-rich coiled-coil protein 1
Gene Name Name: PSRC1
Synonyms:DDA3;ORFNames:FP3214;
Organism Homo sapiens (Human)

PRO ID PR:Q6PGN9
DAG View
PRO Name proline/serine-rich coiled-coil protein 1 (human)
Definition A proline/serine-rich coiled-coil protein 1 that is encoded in the genome of human.
Short Label hPSRC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PGN9 (PSRC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21406692, 21473853
T37 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus   UniProt 23186163
S65 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21473853, 20068231
S70 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 21473853, 18220336, ...19690332, 20068231
S98 Phosphorylation PhosphoSitePlus   UniProt 20068231
S111 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
S122 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S133 Phosphorylation PhosphoSitePlus
S137 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T138 Phosphorylation PhosphoSitePlus
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S142 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S143 Phosphorylation PhosphoSitePlus
T145 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S175 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T177 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S184 Phosphorylation PhosphoSitePlus
S186 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S189 Phosphorylation PhosphoSitePlus
S190 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T193 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S212 Phosphorylation phospho.ELM 18669648, 16964243
S223 Phosphorylation PhosphoSitePlus   RLIMS-P 21473853
S225 Phosphorylation PhosphoSitePlus   RLIMS-P 27697924, 20117088
S239 Phosphorylation PhosphoSitePlus
T245 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16964243
R301 Methylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation HPRD 19691289, 20068231
S70 Phosphorylation HPRD 19664994, 20068231
S98 Phosphorylation HPRD 20068231
S122 Phosphorylation HPRD 20068231
S137 Phosphorylation HPRD 18669648
S140 Phosphorylation HPRD 18669648
S142 Phosphorylation HPRD 18669648
T145 Phosphorylation HPRD 18669648
S175 Phosphorylation HPRD 18669648, 20068231
T177 Phosphorylation HPRD 18669648
S186 Phosphorylation HPRD 18669648, 20068231
S190 Phosphorylation HPRD 18669648, 20068231
T193 Phosphorylation HPRD 18669648, 20068231
S212 Phosphorylation HPRD 18669648, 16964243, 20068231, ...19691289
T215 Phosphorylation HPRD 18669648, 16964243, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation HPRD 19691289, 20068231
S70 Phosphorylation HPRD 19664994, 20068231
S98 Phosphorylation HPRD 20068231
S122 Phosphorylation HPRD 20068231
S137 Phosphorylation HPRD 18669648
S140 Phosphorylation HPRD 18669648
S142 Phosphorylation HPRD 18669648
T145 Phosphorylation HPRD 18669648
S175 Phosphorylation HPRD 18669648, 20068231
T177 Phosphorylation HPRD 18669648
S186 Phosphorylation HPRD 18669648, 20068231
S190 Phosphorylation HPRD 18669648, 20068231
T193 Phosphorylation HPRD 18669648, 20068231
S286 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S65 C65 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
T145 M145 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T193 N193 Biomuta DOID:3571 / liver cancer [ icgc ]
T245 N245 Biomuta DOID:3571 / liver cancer [ icgc ]
T346 N346 Biomuta DOID:3571 / liver cancer [ icgc ]