iPTMnet Report for Q6PGN9 (PSRC1)
Protein Information
| UniProt AC / UniProt ID | Q6PGN9 / PSRC1_HUMAN |
| Protein Name | Proline/serine-rich coiled-coil protein 1 |
| Gene Name | Name: PSRC1 Synonyms:DDA3;ORFNames:FP3214; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6PGN9 |
| PRO Name | proline/serine-rich coiled-coil protein 1 (human) |
| Definition | A proline/serine-rich coiled-coil protein 1 that is encoded in the genome of human. |
| Short Label | hPSRC1 |
| Category | organism-gene |
Q6PGN9 (PSRC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S22 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| T37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| L42 | Phosphorylation | score1 | UniProt | 16964243, 20068231 | ||
| G45 | Phosphorylation | score1 | UniProt | 16964243, 20068231 | ||
| S47 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S65 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S70 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 19690332, 20068231, ... | ||
| S98 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S122 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18220336 | ||
| S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S142 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T145 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S175 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T177 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S186 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S190 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| T193 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S212 | Phosphorylation | score2 | phospho.ELM UniProt | 18669648, 16964243, 20068231 | ||
| T215 | Phosphorylation | score1 | UniProt | 16964243, 20068231 | ||
| S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 27697924, 20117088 | ||
| S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T245 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 16964243 | ||
| R301 | Methylation | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T311 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T346 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S65 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| S70 | Phosphorylation | score0 | HPRD | 19664994, 20068231 | ||
| S98 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S137 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S140 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S142 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T145 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648 | ||
| S175 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T177 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S186 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S190 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T193 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S212 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 16964243, 20068231, ... | ||
| T215 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 16964243, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S65 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| S70 | Phosphorylation | score0 | HPRD | 19664994, 20068231 | ||
| S98 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S137 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S140 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S142 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T145 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S175 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T177 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S186 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S190 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T193 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S292 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S47 | F47 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S65 | C65 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc, cosmic, icgc ] | |
| T145 | M145 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S286 | F286 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| S308 | F308 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S308 | Y308 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
DAG View